Fibre Optics Dissolution System

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Now there's an easy way to bring the power, accuracy and sheer speed of fiber optic technology to your dissolution research. The new Fiber Optics Dissolution System is a complete package that provides immediate data points from all specimens for dissolution rate analysis. Ideal for formulations labs and method development teams investigating immediate release products, this system includes the Hanson SR8-Plus Dissolution Test Station, C Technologies IO Fiber Optic Analysis System (featuring a Varian Cary 50 UV/VIS Spectrophotometer), and a complete System Validation Package.

Advantages of the Hanson System

• Complete fiber optic dissolution system providing everything you need for research, method development and quality control programs.
• Fiber optic technology eliminates the need to remove samples. The concentration of dissolved constituent is measured in situ, directly in the vessel.
• Immediate data points are provided from all specimens for comprehensive dissolution rate analysis.
• Ideal research tool for formulations teams investigating drug release characteristics and variances caused by formula modifications.
• System components include industry-proven Hanson SR8-Plus dissolution tester, C Technologies fiber optic system, and Varian Cary 50 detector.
• Hanson E-Probes automatically drop fiber optic probes to specified sampling position in vessels, then return back to media level after sample analysis.
• A single scanning UV/VIS spectrophotometer eliminates stray light problems as well as the need for cross-calibration and corrections common with other fiber optic systems.
• An extensive data acquisition and analysis software package is included with the fully-loaded PC workstation.
• A complete system validation package is available. Hanson and C Tech/Varian software is USP/FDA compliant, including 21CFR11.

AutoPlus Online UV/VIS Autosampler

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The Hanson AutoPlus is a new precision syringe-pump sampling system for dissolution testing and analysis. The AutoPlus represents thirty years of dissolution test know-how at Hanson Research. We were the first in the business with a dissolution bath in 1969 and a fully automated dissolution test system in 1975. Our precision syringe-pump sampling systems began with the Microette in 1991, and were enhanced with the Waters Transfer Module in 1998. These new AutoPlus systems bring autosampling power, performance and throughput to the modern pharmaceutical lab that is unequalled in the dissolution industry.

The basic AutoPlus platform consists of a choice of 6 or 8 precision glass sampling syringes, with internal valve interfacing, driven by a stepper motor control, in one compact ergonomic instrument package. Teflon tubing harnesses connect up to 3 dissolution baths, along with multi-cell changers for on-line UV/VIS sample analysis, as well as collection trays for sample archive. Easy-Icon programming with graphical display provides a wide range of dissolution test applications, including detect and collect, multi-bath sampling, and routines for set-up, cleaning, validation, 21CFR11, and diagnostics.

The AutoPlus is designed to interface with the Agilent 8453 ChemStation and other modern spectrophotometers with multi-cell capability, and includes communications protocols via contact closure, RS232 and dynamic data exchange (DDE). Similar to the Hanson SR8-Plus "virtual instrument" programming, the AutoPlus is a smart device that anticipates user requirements for set-up, test run, sample throughput and validation. User-friendly features include protocol memory with password protection, continuous display of test conditions and status, user prompts and help screens (ideal for training). The AutoPlus maximizes laboratory efficiency by handling extensive methods, problem drugs, surfactants and other media.